Placenta Accreta Spectrum Disorder: Uterine Dehiscence, Not Placental Invasion

Brett D Einerson1, Jessica Comstock, Robert M Silver

  • 1Departments of Obstetrics and Gynecology, Pathology, and Radiology, University of Utah Health, Intermountain Healthcare, and Primary Children's Hospital, Salt Lake City, Utah.

For decades, placenta accreta spectrum disorder has been classified, staged, and described as a disorder of placental invasion. In this commentary, we argue that placenta accreta spectrum exists as a disorder of defective decidua and uterine scar dehiscence, not as a disorder of destructive trophoblast invasion. Adopting this understanding of placenta accreta spectrum will help direct research efforts and clinical resources toward the prevention, accurate diagnosis, and safe treatment of this devastating-and increasingly common-disorder.

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