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Updated: Dec 24, 2025

Induction and Phenotyping of Acute Right Heart Failure in a Large Animal Model of Chronic Thromboembolic Pulmonary Hypertension
Published on: March 17, 2022
Right Heart Failure: A Hemodynamic Review.
Milad C El Hajj1, Michael C Viray2, Ryan J Tedford2
1Department of Medicine, Internal Medicine, Medical University of South Carolina, 96 Jonathan Lucas Street, Suite 807, Charleston, SC 29425-8900, USA.
The right ventricle, once overlooked, is now recognized as crucial for predicting outcomes in various heart conditions. This review covers key methods for assessing right ventricular function in health and disease.
Area of Science:
- Cardiology
- Cardiovascular Physiology
Background:
- Historically, the right ventricle's role was underestimated, viewed primarily as a blood conduit to the lungs.
- Recent findings highlight its significance in prognostication for left heart failure, pulmonary hypertension, and post-left ventricular assist device implantation.
Purpose of the Study:
- To review traditional and gold-standard hemodynamic assessment methods for the right ventricle.
- To emphasize the renewed clinical interest in quantifying right ventricular function.
Main Methods:
- Review of established hemodynamic assessment techniques.
- Discussion of gold-standard methods for evaluating right ventricular performance.
Main Results:
- The article synthesizes current knowledge on right ventricular assessment.
- It underscores the shift from viewing the right ventricle as a passive conduit to recognizing its active role in cardiac health.
Conclusions:
- Accurate quantification of right ventricular function is essential for patient prognosis.
- Understanding right ventricular hemodynamics is critical in managing complex cardiovascular diseases.
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