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Calnexin cycle - structural features of the ER chaperone system

Guennadi Kozlov1, Kalle Gehring1

  • 1From the Department of Biochemistry & Centre for Structural Biology, McGill University, Montréal, QC, Canada.

The FEBS Journal
|April 15, 2020
PubMed
Summary

The calnexin cycle in the endoplasmic reticulum aids in folding N-glycosylated proteins. Structural studies reveal how chaperones like calnexin and UGGT ensure proper protein folding and quality control.

Keywords:
CypBERp29ERp57PDIUGGTcalnexincalnexin cyclecalreticulinendoplasmic reticulumprotein folding

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