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Chemotherapy-induced peripheral neuropathy (CIPN) is a serious side effect of cancer treatment. This review equips nurses with evidence for assessing, managing, and critically evaluating CIPN care.

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Area of Science:

  • Oncology Nursing
  • Neuroscience
  • Evidence-Based Practice

Background:

  • Chemotherapy-induced peripheral neuropathy (CIPN) presents significant challenges for patients undergoing neurotoxic chemotherapy.
  • Symptoms include numbness, tingling, neuropathic pain, and motor/autonomic dysfunction.
  • CIPN remains an unsolved clinical problem with potential life-compromising consequences.

Purpose of the Study:

  • To synthesize evidence to prepare nurses for comprehensive assessment and supportive care of CIPN.
  • To critically evaluate nursing-relevant literature on CIPN assessment, prevention, and management.
  • To highlight the importance of evidence appraisal for patient safety and financial well-being.

Main Methods:

  • Systematic literature review and evidence synthesis.
  • Focus on nursing-relevant research and clinical practice guidelines.
  • Analysis of prevalence, risk factors, mechanisms, and management strategies for CIPN.

Main Results:

  • Discussion of CIPN prevalence, significance, and characteristics.
  • Overview of underlying mechanisms and identified risk factors.
  • Presentation of nursing-focused evidence for assessment, prevention, and management.

Conclusions:

  • Nurses require comprehensive knowledge to effectively manage CIPN.
  • Critical evaluation of research is essential before implementing interventions.
  • Evidence-based practice in CIPN care can mitigate patient harm and healthcare costs.