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Spectroscopy with computational analysis in virological studies: A decade (2006-2016).
Marfran C D Santos1, Camilo L M Morais1, Yasmin M Nascimento2,3
1Biological Chemistry and Chemometrics, Institute of Chemistry, Federal University of Rio Grande Do Norte, Natal 59072-970, RN, Brazil.
Trends in Analytical Chemistry : TRAC
|April 15, 2020
Summary
Spectroscopic methods offer a rapid, non-destructive approach for analyzing viral samples. This review highlights their utility in virology research and potential for future disease diagnostics.
Area of Science:
- Biophysics
- Analytical Chemistry
- Molecular Biology
Background:
- Spectroscopic methods are sensitive to biochemical variations.
- Techniques are non-destructive, fast, and require minimal sample preparation.
- These attributes make them valuable for biological studies, including virology.
Purpose of the Study:
- To review the application of spectroscopic methods in virology over the past decade (2006-2016).
- To highlight the role of chemometrics in analyzing spectroscopic data for viral samples.
- To suggest novel spectroscopic techniques for future virological research and diagnostics.
Main Methods:
- Retrospective analysis of studies utilizing spectroscopic techniques in virology.
- Review of chemometric algorithms applied to spectroscopic data in virological research.
- Identification of underutilized spectroscopic methods for potential virology applications.
Main Results:
- Spectroscopic techniques have been increasingly employed in virology research.
- Chemometric algorithms effectively analyze spectral data for sample discrimination and classification.
- The review identifies promising spectroscopic approaches for future virological studies.
Conclusions:
- Spectroscopic methods are powerful, versatile tools for virology research.
- Chemometrics enhances the analytical capabilities of spectroscopy in this field.
- Spectroscopy holds significant potential for developing future viral disease diagnostic tools.
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