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A Lego®-like swappable fluidic module for bio-chem applications
Yi-Fan Hsieh1, An-Shik Yang2, Jia-Wei Chen3
1Biomedical Technology and Device Research Laboratories, Industrial Technology Research Institute, Hsinchu 31040, Taiwan.
Sensors and Actuators. B, Chemical
|April 15, 2020
Summary
Researchers developed a modular fluidic system (SFM) with swappable components for rapid assembly of portable, disposable devices. This system enables electricity-free fluid delivery and rapid mixing for microfluidic applications.
Area of Science:
- Microfluidics
- Modular Systems Engineering
- Nanomaterial Synthesis
- Molecular Diagnostics
Background:
- Traditional microfluidic systems can be complex to assemble and customize.
- The need for portable, disposable, and rapidly deployable fluidic devices is increasing in various scientific fields.
Purpose of the Study:
- To design and fabricate a Lego-like swappable fluidic module (SFM) system.
- To enable rapid assembly of portable, disposable fluidic devices with electricity-free operation.
- To demonstrate the versatility of the SFM in microfluidic applications.
Main Methods:
- Modular design and fabrication of functional and auxiliary fluidic components.
- Integration of finger-operated, electricity-free pumps for fluid delivery.
- Utilization of a vortex mixer for rapid, one-shot liquid mixing.
- Application of the SFM in gold nanoparticle synthesis and Hepatitis B virus nucleic acid amplification.
Main Results:
- Successful development of a swappable fluidic module (SFM) system.
- Demonstrated rapid assembly of portable, disposable fluidic systems.
- Validated electricity-free fluid delivery and efficient liquid mixing.
- Successful application in gold nanoparticle synthesis and Hepatitis B virus detection via capillary convective polymerase chain reaction (ccPCR).
Conclusions:
- The proposed SFM offers a flexible and efficient platform for constructing customized microfluidic devices.
- The system facilitates rapid prototyping and deployment of portable, disposable fluidic solutions.
- SFM demonstrates significant potential for diverse applications in chemical synthesis and molecular diagnostics.
