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Related Concept Videos

Biopharmaceutical Factors Influencing Drug Product Design: Overview01:22

Biopharmaceutical Factors Influencing Drug Product Design: Overview

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Rational drug product design integrates knowledge of the drug’s physicochemical properties, formulation components, manufacturing techniques, and intended route of administration. Each factor influences the drug’s performance, including how it is released, absorbed, and eliminated in the body.The physicochemical properties of a drug—such as solubility, stability, and particle size—affect its compatibility with excipients and the choice of dosage form. Excipients, though...
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Structure-Activity Relationships and Drug Design01:28

Structure-Activity Relationships and Drug Design

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Drug design is a dynamic field that involves discovering and developing new medications based on specific biological targets. This process heavily relies on structure-activity relationships (SAR) and quantitative structure-activity relationships (QSAR) to guide the design and optimization of efficient drugs.
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence...
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Clinically Relevant Drug Product Specifications: Methods of Establishment01:29

Clinically Relevant Drug Product Specifications: Methods of Establishment

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Product specifications define the acceptable quality of a pharmaceutical product by ensuring identity, purity, potency, and strength. These specifications serve as benchmarks during development, manufacturing, and post-approval quality control. Clinically relevant specifications are particularly important because they directly relate to a drug's safety and efficacy in clinical use.Dissolution studies are critical biopharmaceutic tools that link in vitro behavior to in vivo performance. They...
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Drug Nomenclature01:17

Drug Nomenclature

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During the development of a new pharmaceutical, the manufacturer initially assigns a code name to the drug. Once approved, the drug receives a United States Adopted Name (USAN)—a generic, nonproprietary designation. Upon being listed in the United States Pharmacopeia, this nonproprietary name becomes the drug's official name. Additionally, the manufacturer assigns a proprietary name or trademark, which serves as the brand name under which the drug is marketed. It is worth noting that...
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Factors Influencing Drug Absorption: Pharmaceutical Parameters01:28

Factors Influencing Drug Absorption: Pharmaceutical Parameters

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Solid dosage forms such as tablets and capsules undergo rigorous manufacturing processes to ensure stability and effectiveness. Their dissolution and absorption properties are influenced significantly by the choice of excipients (inactive ingredients that serve various roles in the formulation), and the methodology applied during production. The manufacturing parameters, such as compression force and granulation techniques, significantly affect dissolution rates. Elevated compression forces...
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Prescription, Nonprescription and Orphan Drugs01:02

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Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
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Related Experiment Video

Updated: Dec 24, 2025

Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting
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Natural products: Designing Russian medications.

V A Stonik, G A Tolstikov

    Herald of the Russian Academy of Sciences
    |April 15, 2020
    PubMed
    Summary

    This research explores natural products, or low-molecular bioregulators, focusing on their isolation, structure identification, and biological functions. Understanding these compounds is crucial for developing new drugs and food additives.

    Area of Science:

    • Interdisciplinary research at the intersection of biology and chemistry.
    • Natural products chemistry and pharmacology.
    • Biochemistry and molecular biology of bioregulators.

    Background:

    • Natural products are vital low-molecular bioregulators.
    • Their study bridges fundamental biological and chemical knowledge.
    • These compounds form the basis for novel therapeutic and nutritional agents.

    Purpose of the Study:

    • To investigate the isolation, structure elucidation, and biological functions of natural products.
    • To explore chemical conversions of natural compounds, particularly those yielding highly active substances.
    • To deepen understanding of bioregulators for drug discovery and food additive development.

    Main Methods:

    • Literature review and synthesis of existing research findings.
    Keywords:
    GinsenosidesGlycyrrhizic AcidNatural ProductResveratrolTriterpene Glycoside

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  • Analysis of chemical structures and biological activities of natural compounds.
  • Discussion of chemical transformations and their outcomes.

    • Main Results:

    • Summarizes key findings on natural products discussed at a RAS Presidium session.
    • Highlights the importance of identifying and characterizing these bioregulators.
    • Emphasizes the potential for discovering highly active products through chemical modification.

    Conclusions:

    • The study of natural products is essential for advancing biological and chemical sciences.
    • Research in this area provides a foundation for creating new pharmaceuticals and functional food ingredients.
    • Continued investigation into natural compounds and their conversions holds significant promise.