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P Ciruela1, C Izquierdo1, M Oviedo1

  • 1Direcció General de Salut Pública. Departament de Sanitat i Seguretat Social. Barcelona. España.

Vacunas
|April 15, 2020
PubMed
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Rotavirus is the primary cause of viral acute gastroenteritis (AGE) in young children, particularly infants, with a winter predominance. Adenovirus 40-41 also affects young children, with higher incidence in autumn. Vaccination against rotavirus is crucial.

Area of Science:

  • Virology
  • Pediatric Infectious Diseases
  • Public Health Surveillance

Context:

  • Rotavirus is a leading cause of severe diarrhea in children under five, contributing significantly to global child morbidity and mortality.
  • Enteric viral infections pose a substantial public health challenge, necessitating accurate etiological data for effective management.

Purpose:

  • To determine the etiology of enteric viruses, specifically rotavirus and adenovirus 40-41, within the Catalan Microbiology Notification System (CMNS).
  • To evaluate the epidemiological importance and disease burden of rotavirus and adenovirus 40-41 in pediatric acute gastroenteritis (AGE).

Summary:

  • Rotavirus accounted for 94.3% of viral AGE cases, predominantly in children under two years old and during winter months.
  • Adenovirus 40-41 represented 5.7% of cases, also primarily affecting children under two, with a higher prevalence in autumn.
Keywords:
Enteric adenovirusRotavirusViral gastroenteritis

Related Experiment Videos

  • Rotavirus and adenovirus 40-41 were significant etiological agents in children under five, ranking second and fourth respectively among bacterial and viral enteritis pathogens.

    • Impact:

    • The findings underscore rotavirus as the principal viral agent of AGE in infants and young children, highlighting the need for vaccination.
    • Understanding the seasonality and age distribution of rotavirus and adenovirus 40-41 aids in public health planning and resource allocation.
    • This study emphasizes the importance of systematic viral detection for a comprehensive understanding of enteric disease epidemiology.