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Updated: Dec 24, 2025
03:23
Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
1.2K
[Eosinophilia in pulmonary infections]
A Moeser1, M W Pletz1, S Schmiedel2
11Institut für Infektionsmedizin und Krankenhaushygiene, Universitätsklinikum Jena, Am Klinikum 1, 07747 Jena, Deutschland.
Der Pneumologe
|April 15, 2020
Summary
Eosinophilia in returned travelers often stems from parasitic infections. Diagnosis involves stool exams, serology, and imaging, with molecular techniques offering higher sensitivity for detecting worm eggs.
Area of Science:
- Tropical medicine
- Parasitology
- Clinical diagnostics
Context:
- Eosinophilia presents a diagnostic challenge with diverse etiologies including allergies, autoimmune conditions, and infections.
- Parasitic infections are the leading cause of eosinophilia in travelers returning from tropical regions.
- The degree of eosinophilia can indicate the specific pathogen involved.
Purpose:
- To outline the diagnostic approach for eosinophilia in travelers from the tropics.
- To highlight the role of parasitic infections as a primary cause.
- To discuss both traditional and novel diagnostic methods.
Summary:
- Diagnostic strategies include multiple stool examinations for helminth eggs and serological tests.
- Imaging studies like chest X-rays, abdominal ultrasounds, and ECGs assess organ involvement.
- Advanced molecular techniques, such as multiplex PCR, enhance the sensitivity of detecting intestinal parasites in stool samples.
- Non-parasitic causes like fungal infections (Cryptococcosis, endemic mycoses, invasive molds) can also induce eosinophilia.
Impact:
- Improved diagnostic accuracy for eosinophilia in returning travelers.
- Facilitates timely and appropriate treatment of tropical-acquired infections.
- Highlights the clinical utility of advanced molecular diagnostics in parasitology.
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