Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanical Ventilation II: Invasive Ventilation01:23

Mechanical Ventilation II: Invasive Ventilation

524
Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
524
Ventilatory Modes01:14

Ventilatory Modes

1.1K
Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
1.1K
Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

442
Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...
442
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

372
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
372
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

911
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
911
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

661
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
661

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.

The EMBO journal·1995
Same author

Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites.

The Journal of biological chemistry·1995
Same author

Recurrent and novel LDL receptor gene mutations causing heterozygous familial hypercholesterolemia in La Habana.

Human genetics·1995
Same author

Structure and promoter characterization of the human stromelysin-3 gene.

The Journal of biological chemistry·1995
Same author

Frequent loss of heterozygosity on chromosome 9, and low incidence of mutations of cyclin-dependent kinase inhibitors p15 (MTS2) and p16 (MTS1) genes in gliomas.

Oncogene·1995
Same author

Molecular analysis of genetic changes in ependymomas.

Genes, chromosomes & cancer·1995
Same journal

[Acute disseminated encephalomyelitis and severe post-infectious encephalitis].

Reanimation : journal de la Societe de reanimation de langue francaise·2020
Same journal

Reanimation : journal de la Societe de reanimation de langue francaise·2020
Same journal

[Consequences of the SARS outbreak on the Health Care System in Ontario].

Reanimation : journal de la Societe de reanimation de langue francaise·2020
Same journal

[Current techniques used for the diagnosis of respiratory virus infectious in intensive care units].

Reanimation : journal de la Societe de reanimation de langue francaise·2020
Same journal

[Modulation of transcriptomic signature of the infected host: a new therapeutic strategy for the management of severe viral infections? Example of the flu].

Reanimation : journal de la Societe de reanimation de langue francaise·2020
Same journal

[Is control fever mandatory in severe infections?]

Reanimation : journal de la Societe de reanimation de langue francaise·2020
See all related articles

Related Experiment Video

Updated: Dec 24, 2025

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
04:32

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia

Published on: June 28, 2018

12.3K

[Ventilator-associated viral pneumonia].

L Chiche1, G Thomas1, J-M Forel1

  • 1Service de réanimation-médicale, URMITE CNRS-UMR 6236, CHU Nord, Assistance publique-Hôpitaux de Marseille, université Aix-Marseille-II, Chemin-des-Bourrely, F-13015 Marseille cedex 20, Marseille, France.

Reanimation : Journal De La Societe De Reanimation De Langue Francaise
|April 15, 2020
PubMed
Summary
This summary is machine-generated.

Viral infections are common in critically ill patients. This review examines the role of viruses like Herpesviridae in causing ventilator-associated pneumonia in intensive care units.

Keywords:
CytomegalovirusHerpes simplex virusIntensive care unitMechanical VentilationPneumoniaVirus

More Related Videos

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
05:39

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia

Published on: May 26, 2023

2.1K
Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS
06:22

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS

Published on: April 7, 2021

3.7K

Related Experiment Videos

Last Updated: Dec 24, 2025

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
04:32

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia

Published on: June 28, 2018

12.3K
Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
05:39

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia

Published on: May 26, 2023

2.1K
Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS
06:22

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS

Published on: April 7, 2021

3.7K

Area of Science:

  • Critical care medicine
  • Infectious diseases
  • Virology

Context:

  • Viral infections, particularly respiratory ones, are frequently observed in critically ill, non-immunocompromised patients.
  • Advanced diagnostic tools like polymerase chain reaction (PCR) enable rapid viral detection.
  • Herpesviridae, including herpes simplex virus and cytomegalovirus, are commonly identified in intensive care unit (ICU) patients.

Purpose:

  • To evaluate the role of viral infections in the development of mechanical ventilation-acquired pneumonias (VAP) in non-immunocompromised adult ICU patients.
  • To explore the potential pathophysiology of these viral VAPs.
  • To discuss the feasibility and potential benefits of therapeutic interventions for viral VAPs.

Summary:

  • This review assesses the contribution of viral pathogens to VAP in non-immunocompromised ICU patients.
  • It highlights the prevalence of Herpesviridae and discusses diagnostic approaches.
  • The review also delves into the mechanisms of viral VAP and potential treatment strategies.

Impact:

  • Provides a comprehensive overview of viral VAP in a critical care setting.
  • Informs clinical decision-making regarding the diagnosis and management of VAP.
  • Highlights areas for future research into viral VAP pathophysiology and treatment.