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Updated: Dec 24, 2025
09:49
Experimental Model to Evaluate Resolution of Pneumonia
Published on: February 17, 2023
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[Acute fibrinous and organizing pneumonia].
Cláudia Santos1, Fátima Fradinho2, Alexandra Catarino2
1Interna Complementar de Pneumologia.
Revista Portuguesa De Pneumologia
|April 15, 2020
Summary
Acute Fibrinous and Organizing Pneumonia (AFOP) is a distinct interstitial lung disease. This review and case study highlight its unique features compared to other acute lung injuries.
Area of Science:
- Pulmonary Pathology
- Histopathology
- Interstitial Lung Diseases
Context:
- Acute Fibrinous and Organizing Pneumonia (AFOP) is a distinct histologic pattern.
- It presents with intra-alveolar fibrin and diffuse organizing pneumonia.
- AFOP requires differentiation from other acute lung injury patterns like DAD, OP, and EP.
Purpose:
- To review the literature on AFOP.
- To describe a clinical case with unusual imaging and outcome.
- To enhance understanding of this interstitial pulmonary disease.
Summary:
- AFOP is characterized by fibrin "balls" and diffuse organizing pneumonia.
- Symptoms can be acute or subacute.
- This condition is histologically distinct from Diffuse Alveolar Damage (DAD), Organizing Pneumonia (OP), and Eosinophilic Pneumonia (EP).
Impact:
- Improves diagnostic criteria for AFOP.
- Highlights the importance of distinguishing AFOP from other acute lung conditions.
- Provides insights into the clinical presentation and management of AFOP.
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