Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

558
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
558
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

696
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
696
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy01:16

Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy

940
Helicobacter pylori, a resilient gram-negative bacterium, can thrive in the stomach's harsh, acidic environment. Infection with H. pylori leads to a cascade of events within the stomach lining. One of the critical disruptions caused by this bacterium is the interference with somatostatin production, a hormone responsible for regulating acid secretion. This interference tips the balance, escalating acid secretion and diminishing bicarbonate levels. This imbalance compromises the defensive...
940
Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

532
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
532
Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

600
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
600
Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

581
Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
581

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinician characteristics associated with CT use in children with minor blunt head trauma at very low risk for clinically important traumatic brain injuries.

Emergency medicine journal : EMJ·2026
Same author

Psychometric Evaluation of a NICU Version of the Family-Centered Care Experience Survey.

Hospital pediatrics·2026
Same author

Video vs Telephone Consultations for Pediatric Quality of Care in Emergency Departments.

Pediatrics·2026
Same author

GAIN: a multicenter pilot protocol for early initiation of enteral feeds in neonates with simple gastroschisis.

Pilot and feasibility studies·2026
Same author

Views on democracy and political violence in the United States in 2025: findings from a nationally representative survey.

Injury epidemiology·2026
Same author

Support for authoritarianism and use of force by and against the federal government in the United States in mid-2025: findings from a nationally representative survey.

Injury epidemiology·2026

Related Experiment Video

Updated: Dec 24, 2025

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods
08:38

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods

Published on: September 10, 2016

25.1K

Probiotics as a Tx resource in primary care.

Daniel J Merenstein1, Mary Ellen Sanders2, Daniel J Tancredi3

  • 1Georgetown University Medical Center, Washington, DC, USA.

The Journal of Family Practice
|April 15, 2020
PubMed
Summary

Clinicians can recommend probiotics based on scientific evidence, even though they are not regulated as drugs. This approach ensures informed patient care and supports the evidence-based use of probiotics.

More Related Videos

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
07:06

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

27.6K
Probiotic Studies in Neonatal Mice Using Gavage
10:36

Probiotic Studies in Neonatal Mice Using Gavage

Published on: January 27, 2019

20.5K

Related Experiment Videos

Last Updated: Dec 24, 2025

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods
08:38

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods

Published on: September 10, 2016

25.1K
Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
07:06

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

27.6K
Probiotic Studies in Neonatal Mice Using Gavage
10:36

Probiotic Studies in Neonatal Mice Using Gavage

Published on: January 27, 2019

20.5K

Area of Science:

  • Microbiology
  • Gastroenterology
  • Clinical Medicine

Background:

  • Probiotics are live microorganisms intended to confer a health benefit when administered in adequate amounts.
  • Currently, probiotics are typically marketed as dietary supplements rather than pharmaceutical drugs.
  • This regulatory status presents challenges for evidence-based clinical recommendations.

Purpose of the Study:

  • To explore the feasibility of evidence-based recommendations for probiotics by clinicians.
  • To outline a framework for evaluating probiotic efficacy and safety in a clinical context.
  • To bridge the gap between probiotic research and clinical practice.

Main Methods:

  • Systematic review of clinical trials and meta-analyses on probiotic efficacy.
  • Analysis of regulatory frameworks for probiotics in different regions.
  • Development of criteria for assessing the quality of evidence supporting probiotic use.

Main Results:

  • A significant body of evidence supports the efficacy of specific probiotic strains for certain health conditions.
  • Standardized criteria can be applied to evaluate the scientific rigor of probiotic studies.
  • Clinicians can utilize evidence-based guidelines to make informed recommendations.

Conclusions:

  • Despite not being marketed as drugs, probiotics can be recommended by clinicians using a structured, evidence-based approach.
  • This approach enhances patient safety and optimizes therapeutic outcomes.
  • Further research and clear guidelines are needed to support the integration of probiotics into routine clinical practice.