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Mitophagy in cardiovascular homeostasis.

Ruohan Zhang1, Judith Krigman2, Hongke Luo2

  • 1Departments of Physiology and Cell Biology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA; Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA; College of Pharmacy, Department of Graduate Research, The Ohio State University, Columbus, Ohio, USA.

Mechanisms of Ageing and Development
|April 15, 2020
PubMed
Summary

Mitophagy, a quality control process, clears damaged mitochondria in the heart. This pathway is crucial for maintaining cardiac health and function, offering potential therapeutic targets for cardiovascular diseases.

Keywords:
AutophagyCardiovascular diseaseHeart failureMitochondriaMitophagy

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