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Updated: Dec 24, 2025

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Published on: January 17, 2018
Pituitary Adenomas with Changing Phenotype: A Systematic Review
Fernando Guerrero-Pérez1, Agustina Pia Marengo1, Noemi Vidal2
1Department of Endocrinology, Bellvitge University Hospital, Barcelona, Spain.
Pituitary adenomas (PA) can unexpectedly change their function over time, sometimes switching from hormone-producing to non-functioning or altering their hormonal expression. Lifelong monitoring is crucial for detecting these pituitary tumor transformations.
Area of Science:
- Endocrinology
- Oncology
- Neurosurgery
Background:
- Phenotype transformation in pituitary adenomas (PA) is an uncommon but significant clinical event.
- Understanding these transformations is vital for managing patients with pituitary tumors.
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