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Ophthalmic Timolol and Hospitalization for Symptomatic Bradycardia and Syncope: A Case Series
Syed A Abbas1,2, Syeda M Hamadani2, Umair Ahmad3
1Internal Medicine, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, USA.
Abstract:
Topical beta-blockers are commonly used for the management of primary open angle glaucoma (POAG). One of the rare but serious side effects of the topical beta-blockers is bradycardia, defined as a heart rate below 60 beats per minute. In few cases, the heart rate drops to much lower level resulting in syncope or symptomatic bradycardia. Topical beta-blockers are still widely used for POAG even though there are much better medications available. We present a series of four cases of symptomatic bradycardia resulting from the use of timolol eye drops and after discontinuation of the eye drops, heart rate improved to normal range (60-100 beats per minute).
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