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Disparities in the Use of Atherectomy and Intravascular Lithotripsy for Percutaneous Coronary Intervention
Kyu Lee1, Priya Roy1, Umair Ahmad1
1Division of Cardiovascular Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Insights
Social deprivation is linked to reduced use of atherectomy and intravascular lithotripsy (IVL) during percutaneous coronary intervention (PCI) for calcified coronary disease in the US. This suggests potential disparities in advanced treatment access.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Health Disparities
Background:
- Atherectomy and intravascular lithotripsy (IVL) improve percutaneous coronary intervention (PCI) outcomes in calcified coronary disease.
- Understanding the utilization of these advanced PCI technologies across different socioeconomic strata is crucial.
Purpose of the Study:
- To investigate the association between social deprivation and the use of atherectomy/IVL during PCI for severely calcified lesions.
- To identify potential disparities in access to advanced PCI techniques based on socioeconomic factors.
Main Methods:
- Analysis of 310,124 patients undergoing PCI for severely calcified lesions (2018-2023) from the CathPCI Registry.
- Social Deprivation Index (SDI) calculated based on residential zip codes to quantify area-level socioeconomic disadvantage.
- Hierarchical logistic regression models used to assess the relationship between SDI and atherectomy/IVL utilization.
Main Results:
- Atherectomy/IVL was used in 33.0% of PCI procedures for severely calcified arteries.
- An inverse, graded relationship was observed between higher social deprivation and lower rates of atherectomy/IVL use.
- Patients in higher deprivation quartiles were significantly less likely to receive atherectomy/IVL compared to those in the lowest quartile, even after adjusting for covariates.
Conclusions:
- Greater social deprivation in the United States is associated with decreased utilization of atherectomy and IVL during PCI for calcified coronary artery disease.
- These findings highlight potential inequities in the application of advanced interventional cardiology technologies.
- Further research is needed to address and mitigate these disparities in PCI treatment.
Background:
Atherectomy and intravascular lithotripsy (IVL) facilitate percutaneous coronary intervention (PCI) in calcified coronary disease, and use of these technologies is associated with greater luminal gain and superior intervention success. As atherectomy/IVL gain more widespread acceptance, it is important to understand whether their use differs across levels of social deprivation.
Methods:
Within the National Cardiovascular Data Registry CathPCI Registry, we identified 310,124 patients who had a PCI for severely calcified lesions between 2018 and 2023. For each patient, we determined their social deprivation index (SDI) based on residential zip codes. The SDI is a composite measure of area-level social deprivation, with higher values correlating to greater deprivation. Hierarchical logistic regression models evaluated the association of SDI with use of atherectomy/IVL.
Results:
Mean age was 70.9 ± 10.6 years, 69.4% were men, and 82.3% were of White race. Atherectomy/IVL was used in 33.0% of PCIs in severely calcified arteries. There was an inverse, graded relationship between SDI and atherectomy/IVL use. These differences were only partially attenuated after adjusting for patient and PCI characteristics. Compared with those residing in neighborhoods with the lowest quartile of social deprivation, those in the third and fourth quartiles of social deprivation were 10% (odds ratio, 0.90; 95% CI, 0.88-0.92; P < .001) and 8% (odds ratio, 0.92; 95% CI, 0.90-0.94; P < .001), respectively, less likely to have atherectomy/IVL used during PCI.
Conclusions:
In the United States, greater social deprivation was associated with lower rates of atherectomy/IVL during PCI for severely calcified coronary artery stenoses, highlighting potential disparities in use of these technologies.
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