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Updated: Dec 24, 2025

Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein
Published on: May 30, 2015
A novel, label-free liquid crystal biosensor for Parkinson's disease related alpha-synuclein
Xiuxiu Yang1, Haiyu Li1, Xiaofang Zhao2
1Key Laboratory of Organic Optoelectronics and Molecular Engineering of the Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084, China. zyang@tsinghua.edu.cn.
Abstract:
A liquid crystal biosensor based on DNA aptamer for sensitive detection of Parkinson's Disease (PD) related alpha-synuclein was developed. This LC biosensor is constructed using a simple and label free method, and it not only enables early PD diagnosis, but also provides a general platform for detection based on DNA aptamer.

