Related Experiment Video
Updated: Dec 24, 2025

CO2-Lasertonsillotomy Under Local Anesthesia in Adults
Published on: November 6, 2019
#10-Year Challenge: Local anaesthetic for post-tonsillectomy pain: Update meta-analysis
Darren Yap1, Miane Ng2, Ram Moorthy1
1ENT Department, Wexham Park Hospital, Slough, UK.
Local anesthetic use, whether topical or infiltrated, significantly reduces pain after tonsillectomy. This meta-analysis confirms its effectiveness for managing post-tonsillectomy pain, with no significant adverse effects reported.
Area of Science:
- Anesthesiology
- Otolaryngology
- Pain Management
Background:
- Effective management of post-tonsillectomy pain is crucial for patient recovery.
- Previous meta-analyses indicated local anesthetics reduce postoperative pain.
- Current evidence needed to be reviewed and compared to prior findings.
Purpose of the Study:
- To systematically review current evidence on local anesthetic use for post-tonsillectomy pain.
- To compare current findings with a 2008 meta-analysis.
- To assess the efficacy and safety of local anesthetics in reducing post-tonsillectomy pain.
Main Methods:
- Systematic literature searches were conducted in MEDLINE, EMBASE, and PubMed.
- A meta-analysis of randomized control trials was performed.
- Studies assessed the use of local anesthetic agents for post-tonsillectomy pain.
Main Results:
- Twenty-three studies were included in the meta-analysis.
- Local anesthetic (topical or infiltrated) significantly reduced pain scores compared to controls.
- Pain reduction was significant at 4-6 hours, 24 hours, and 5-7 days post-surgery.
Conclusions:
- Peri-operative local anesthetic use improves post-tonsillectomy pain outcomes.
- Studies were generally small, suggesting a need for larger multi-centered trials.
- No significant adverse side effects were reported with local anesthetic use.
Related Concept Videos
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Local Anesthetics: Pharmacokinetics
Local Anesthetics: Clinical Application as Spinal Anesthesia
Local Anesthetics: Chemistry and Structure-Activity Relationship
Local Anesthetics: Adverse Effects
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...

