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Updated: Dec 24, 2025
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Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
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Cancer fertility preservation: a report from a Brazilian social program
Caroline Z Berton1, Caroline Brogliato1, Ivan H Yoshida1
1Instituto Idéia Fértil de Saúde Reprodutiva, Santo André, SP, Brasil.
JBRA Assisted Reproduction
|April 16, 2020
Summary
Cancer patients can preserve fertility through oocyte cryopreservation before treatment. A Brazilian social program successfully vitrified 2528 oocytes, with one patient achieving pregnancy, demonstrating the viability of fertility preservation.
Area of Science:
- Oncology
- Reproductive Medicine
- Biotechnology
Background:
- Cancer treatments can impair fertility, impacting patients' reproductive future.
- Fertility preservation is crucial for cancer patients of reproductive age.
- Social programs facilitate access to fertility preservation services.
Purpose of the Study:
- To present clinical and laboratory data from a Brazilian social program focused on cancer fertility preservation.
- To evaluate the outcomes of oocyte cryopreservation in cancer patients undergoing oncological treatment.
Main Methods:
- A descriptive observational study was conducted from July 2011 to December 2018.
- 246 cancer patients from a social program in Santo André, Brazil, underwent oocyte cryopreservation.
- Oocytes were vitrified prior to the initiation of cancer treatment.
Main Results:
- 246 patients diagnosed with 27 types of cancer, most commonly breast cancer, participated.
- A total of 2528 MII oocytes were vitrified, averaging 10.3 oocytes per patient.
- Four patients utilized thawed oocytes for in vitro fertilization, with one successful pregnancy achieved.
Conclusions:
- Fertility preservation provides a viable option for cancer patients to maintain future childbearing potential.
- Oncological patients should receive comprehensive counseling regarding fertility preservation options.
- Social programs play a vital role in enabling cancer patients to preserve their fertility.
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