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Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry
Published on: October 2, 2016
[Fast HPLC-MS/MS screening method for identification of illegal drugs including new psychoactive substances and their
S A Savchuk1,2, K M Shestakova2,3, L N Rizvanova4
1Russian Centre of Forensic Medical Expertise of the Ministry of Health of the Russia, Moscow, Russia.
Abstract:
Aim of this study was to develop a fast screening method for identification of illegal drugs including new psychoactive substances and their metabolites in human urine by means of liquid chromatography mass-spectrometry HPLC-MS/MS screening method for identification of 138 psychoactive substances in urine was established, validated and tested. High-resolution mass-spectrometry was used for confirmation of the developed approach. The developed method was tested on 50 positive urine samples containing the target compounds, which proved reliability and accuracy of the established screening method.

