Related Experiment Video
Updated: Dec 23, 2025

Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease
Published on: March 15, 2024
Complex Peyronie's disease cases: surgery with or without penile prosthesis placement
E Fernández-Pascual1, L M Quintana Franco2, A Fraile Poblador3
1Servicio de Urología, Hospital Universitario La Paz, Madrid, España; Lyx Instituto de Urología, Universidad Francisco de Victoria, Madrid, España.
Introduction And Objective:
Surgery is the treatment of choice for patients with Peyronie's disease presenting difficulty in penetration or erectile dysfunction without adequate response to therapy. Several techniques have been described, and urologists must be aware of their possible complications and sequelae in order to offer the patient the best possible alternative.
Patients And Methods:
Three complex cases of patients with Peyronie's disease are presented. The first case exposes a complication after penile plication for the treatment of a major dorsal curve. The second case refers to difficult anal penetration secondary to a problem of erection direction after plaque incision surgery with oral mucosa grafting. The last case is a patient with a late post-operative complication of a three-piece prosthesis placement with plaque incision and equine collagen patch.
Results:
Surgical options for each case are detailed and discussed. After patients were informed, the decision was taken in a consensual manner.
Conclusions:
Surgery for Peyronie's disease requires the urologist's consideration of the functional, aesthetic and psychological spheres. A systematic approach to all of these avoids complications, sequels and improves results.
Related Concept Videos
Urinary Tract Calculi VI: Surgical Management
Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease
Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...

