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Related Experiment Video

Updated: Dec 23, 2025

Probing High-density Functional Protein Microarrays to Detect Protein-protein Interactions

Probing High-density Functional Protein Microarrays to Detect Protein-protein Interactions

Published on: August 2, 2015

Developments and Applications of Functional Protein Microarrays.

Guan-Da Syu¹, Jessica Dunn², Heng Zhu³

¹Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan 701, Taiwan R.O.C..

Molecular & Cellular Proteomics : MCP

|April 19, 2020

Summary

Protein microarrays enable high-throughput protein analysis for applications like drug discovery and biomarker identification. This review covers recent advancements and future directions in protein microarray technology.

Keywords:

Protein array biofluids diagnostic pathogens protein-protein interactions

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Last Updated: Dec 23, 2025

Probing High-density Functional Protein Microarrays to Detect Protein-protein Interactions

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Published on: August 2, 2015

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Kinase Inhibitor Screening In Self-assembled Human Protein Microarrays

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Published on: October 23, 2019

Area of Science:

Biochemistry
Molecular Biology
Proteomics

Background:

Protein microarrays are essential for unbiased, high-throughput protein characterization.
This technology supports diverse applications, including interaction studies, post-translational modification analysis, drug target identification, and biomarker discovery.

Purpose of the Study:

To review advancements in protein microarray technology over the past decade in basic and translational research.
To introduce the novel GPCR-VirD membrane protein array.
To discuss future directions for functional protein microarrays.

Main Methods:

Review of recent literature on protein microarray developments.
Introduction and description of the GPCR-VirD array.
Discussion of emerging trends and future prospects in the field.

Main Results:

Protein microarray technology has seen significant development in the last decade.
The GPCR-VirD array represents a novel tool for membrane protein analysis.
The field is progressing towards more advanced functional protein microarrays.

Conclusions:

Protein microarrays are versatile tools with broad applications in biological and medical research.
Continued innovation is expanding the capabilities of protein microarray technology.
Future research will likely focus on novel array designs and applications, particularly for membrane proteins.