Renal Replacement Lipomatosis-A Rare but Often Underdiagnosed Cause of Progressive Renal Damage in Calculus Disease

Renal replacement lipomatosis is a rare condition characterized by extensive fat deposition in hilum with parenchymal thinning and progressive detoriation of function.^1-4 Though uncommon, it should be considered as a possibility in patients with history of intervention for stone disease.^5,6 Correct diagnosis can be easily established by cross sectional imaging and is helpful to counsel patients about the possibility of progressive functional detoriation and poor salvageability of the affected kidneys.^7-10 Here, we present 2 patients with previous history of intervention for calculus disease who had developed progressive renal damage due to RRL with one patient ultimately needing nephrectomy.