Related Experiment Video
Updated: Dec 23, 2025

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Twitter promotion predicts citation rates of cardiovascular articles: a preliminary analysis from the ESC Journals
Ricardo Ladeiras-Lopes1,2, Sarah Clarke3, Rafael Vidal-Perez4
1Cardiology Department, Gaia/Espinho Hospital Centre and Cardiovascular Research Centre, Faculty of Medicine, University of Porto, Rua Conceicao Fernandes, 4434-502 Vila Nova de Gaia, Portugal.
Aims:
The association between the dissemination of scientific articles on Twitter and online visibility (including Altmetric score) is still controversial and the impact on citation rates has never been addressed for cardiovascular medicine journals.
Methods And Results:
The ESC Journals Study randomized 696 papers published in the ESC Journals family (March 2018-May 2019) for promotion on Twitter or to a control arm (with no active tweeting from ESC channels) and aimed to assess if Twitter promotion was associated with an increase in citation rate (primary endpoint) and Altmetric score. This is a preliminary analysis of 536 articles (77% of total) published until December 2018 (therefore, papers published at least 6 months before collecting citation and Altmetrics data). In the analysis of the primary endpoint, Twitter promotion of articles was associated with a 1.43 (95% confidence interval 1.29-1.58) higher rate of citations, and this effect was independent of the type of article. Both Altmetric score and number of users tweeting were positively associated with the number of citations in both arms, with evidence of a stronger association (interaction) in the Twitter arm.
Conclusion:
Therefore, a social media strategy of Twitter promotion for cardiovascular medicine papers seems to be associated with increased online visibility and higher number of citations. The final analysis will include 696 papers and 2-year scientific citation rate and is estimated to be concluded in March 2021.
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