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Laser Raman spectroscopic study of hereditary cataractous lenses in ICR/f-strain rat
A Mizuno1, E H Kanematsu, H Suzuki
1Department of Biochemistry, Jikei University School of Medicine, Tokyo, Japan.
Japanese Journal of Ophthalmology
|January 1, 1988
Abstract:
The lenses of ICR/f-strain rats with hereditary cataract were monitored in situ by laser Raman spectroscopy. The lenses used were within the age of 3-10 weeks before lens opacification became manifest. The reduction of protein SH group content and the increase of protein S-S bond content were observed in ICR/f rats in the precataractous stage. No significant change in the water content was observed.