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Therapeutic strategies for critically ill patients with COVID-19

Lei Li1, Ranran Li1, Zhixiong Wu2

  • 1Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People's Republic of China.

Annals of Intensive Care
|April 21, 2020
PubMed

Insights

Critical care for COVID-19 patients involves managing severe cases in the ICU. This summary outlines supportive strategies for respiratory and circulatory issues, organ function, and nutrition before specific treatments are available.

Area of Science:

  • Critical care medicine
  • Infectious diseases
  • Virology

Background:

  • The 2019 novel coronavirus (COVID-19) outbreak poses a global health threat.
  • Critically ill COVID-19 patients require intensive management in the Intensive Care Unit (ICU), demanding significant medical resources.

Purpose of the Study:

  • To summarize promising management strategies for COVID-19 patients in the ICU.
  • To provide guidance on treatments before specific vaccines and drugs become available.

Main Methods:

  • Reviewing previous experiences in treating other viral infections and influenza.
  • Summarizing promising drugs and adjunctive agents.
  • Detailing respiratory support, circulation management, and organ function monitoring.
  • Outlining appropriate nutritional strategies.

Main Results:

  • Identification of potential therapeutic drugs and supportive agents.
  • Recommendations for respiratory and circulatory support.
  • Emphasis on multi-organ function monitoring and nutritional support.

Conclusions:

  • The summarized strategies offer a referable approach for managing severe COVID-19 in the ICU.
  • These supportive measures are crucial in the interim period before the availability of specific COVID-19 vaccines and antiviral drugs.

Keywords:
2019-nCoVAdjunctive interventionAntiviral therapyCoronavirusRespiratory support

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