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Updated: Dec 23, 2025

A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome
Published on: October 2, 2018
Ovarian Stromal Hyperplasia: A Rare Cause of Postmenopausal Hyperandrogenism
Teresa Lozoya Araque1, Isauro Rogelio Monfort Ortiz2, José Enrique Martín González3
1Department of Obstetrics and Gynecology, Manises Hospital, Valencia, Spain. telozoar@gmail.com.
Abstract:
Ovarian hyperthecosis and ovarian stromal hyperplasia (OSH) are two uncommon non-neoplastic causes of ovarian hyperandrogenism, whose etiology is still unknown. These conditions are characterized by obesity, hyperinsulinemia, acanthosis nigricans, and even virilization, mainly in postmenopausal women. Here we have reported the case of a 67-year-old patient with a diagnosis of OSH, which was resolved after bilateral laparoscopic oophorectomy. In this case report, we have discussed two different conditions posing a diagnostic challenge and requiring a high index of suspicion.
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