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Related Experiment Video

Updated: Dec 23, 2025

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

Giant Idiopathic Angioid Streaks.

Brijesh Takkar^1,2, Anubha Rathi³, Pradeep Venkatesh⁴

¹Department of Ophthalmology, All India Institute of Medical Sciences, Bhopal, India.

Journal of Ophthalmic & Vision Research

|April 21, 2020

Summary

This case report highlights a rare instance of gigantic idiopathic angioid streaks, potentially exacerbated by past steroid abuse. Advanced imaging confirmed the diagnosis and revealed extensive retinal involvement.

Keywords:

Choroidal Neovascular Membrane Pseudoxanthoma Elasticum Swept Source Optical Coherence Tomography Angioid Streak

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Area of Science:

Ophthalmology
Retinal Diseases

Background:

Idiopathic angioid streaks are a rare condition affecting Bruch's membrane.
Macular choroidal neovascularization (CNVM) and peripheral retinal hemorrhages are potential complications.

Observation:

A young male presented with CNVM and peripheral retinal hemorrhages.
Gigantic angioid streaks extending to the equator were observed in both eyes.
Breaks in the retinal pigment epithelium-Bruch's membrane complex were noted.

Findings:

Swept source optical coherence tomography (SSOCT) and ultrawide field imaging were crucial for diagnosis.
A history of steroid abuse was the only significant systemic finding.
The angioid streaks were idiopathic in origin.

Implications:

Advanced imaging is vital for diagnosing and characterizing extensive angioid streaks.
The potential role of steroid abuse in angioid streak presentation warrants further investigation.
This case expands understanding of the clinical spectrum of idiopathic angioid streaks.