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Composition of urinary calculi: Lessons from a French epidemiologic retrospective study
1Service de biochimie et biologie moléculaire, Centre De Biologie Sud, Hospices Civils de Lyon, hôpital Lyon Sud, Lyon, France.
Summary
Urinary stone composition varies by gender. Whewellite and uric acid stones are more common in men, while carbapatite and struvite stones are more frequent in women.
Area of Science:
- Urology
- Biochemistry
- Epidemiology
Background:
- Urolithiasis (urinary stone disease) is a prevalent urological condition with increasing incidence in developed nations.
- Understanding the composition of urinary calculi is crucial for managing this disease.
Purpose of the Study:
- To investigate the relationship between urinary stone composition, patient age, and gender in a French population.
- To provide updated epidemiological data on urinary calculi in France.
Main Methods:
- A retrospective cohort study analyzed 5782 urinary calculi samples from 2013-2017.
- Data on stone composition, papillary umbilication, Randall's plaque, age, and gender were collected.
- Statistical analysis employed the Chi-squared test.
Main Results:
- The male to female sex ratio was 1.76, with an average age of 52.1 years.
- Whewhellite (44.4%) was the most common stone component, followed by carbapatite (14.0%), weddellite (13.4%), and uric acid (13.0%).
- Significant gender differences were observed: whewellite and uric acid were more frequent in men, while carbapatite and struvite predominated in women (P<0.001).
Conclusions:
- This study offers recent insights into urinary stone composition in a French population.
- Specific stone compositions show significant associations with gender, aiding in understanding urolithiasis etiology.
Keywords:
Analyse morpho-constitutionnelleCalculs urinairesEpidemiologyFranceLithiase urinaireMorpho-constitutional analysisUrinary calculiUrolithiasisÉpidémiologieMore Related Videos
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