Related Experiment Video
Updated: Dec 23, 2025

Rat Model of Adhesive Capsulitis of the Shoulder
Published on: September 28, 2018
Shoulder Conditions: Glenohumeral Joint Osteoarthritis and Adhesive Capsulitis
Jill Tirabassi1, Giselle Aerni2
1UMass Memorial HealthAlliance-Clinton Hospital Burbank Campus, 275 Nichols Road, Fitchburg, MA, 01420.
Abstract:
Glenohumeral joint osteoarthritis (OA) and adhesive capsulitis are two common causes of shoulder pain. The glenohumeral joint is the third most common large joint affected by OA. Studies have shown that 16% to 20% of adults older than 65 years have radiographic signs of glenohumeral joint OA. Management of shoulder OA starts with conservative therapies, including oral drugs, injections, and physical therapy. Joint replacement can be considered if conservative measures are not effective. Adhesive capsulitis, also known as frozen shoulder, is estimated to affect 2% to 5% of the population and is seen most often in patients between ages 40 and 65 years. The exact causal mechanism of adhesive capsulitis is unknown but risk factors include diabetes and thyroid disease. Adhesive capsulitis is thought to follow a set of clinical stages. It ultimately is self-limited, although some patients experience residual effects. Management starts with conservative therapies, including oral drugs, injections, and physical therapy. Surgical management can be considered if conservative measures are not effective.
Related Concept Videos
Muscles of the Shoulder
Anterior Thoracic Muscles
The anterior thoracic muscles include the serratus anterior, subclavius, and...
Bones of the Upper Limb: Humerus
Structural Joints: Synovial Joints
Joints
Structural joint classifications are based on the material that makes up the joint as well as whether or not the joint contains a space between the bones. Joints are structurally classified as fibrous, cartilaginous, or synovial.
Fibrous Joints Are Immovable
The bones of a...
Muscles that Move the Arm
The pectoralis major has two origins. Its clavicular head originates on the medial half of the clavicle. In contrast, the sternocostal head originates on the costal cartilages of ribs 1-6, the sternum, and the aponeurosis of the external oblique of the...
Functional Classification of Joints
The functional classification of joints is determined by the amount of mobility between the adjacent bones. Joints are functionally classified as a synarthrosis or immobile joint, an amphiarthrosis or slightly moveable joint, or as a diarthrosis, a freely moveable joint. Fibrous and cartilaginous joints can be functionally classified as either synarthroses or amphiarthroses, whereas all synovial joints are classified as diarthroses.
Synarthrosis
An...

