Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Photoluminescence: Applications01:14

Photoluminescence: Applications

917
Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...
917
Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

12.1K
Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...
12.1K
Fluorescence and Phosphorescence: Instrumentation01:25

Fluorescence and Phosphorescence: Instrumentation

1.3K
Fluorometers and spectrofluorometers are two types of instruments used for measuring molecular fluorescence. These instruments differ in how they select excitation and emission wavelengths and the type of light sources they utilize. Fluorometers use absorption interference filters to choose excitation and emission wavelengths. The excitation source in a fluorometer is typically a low-pressure mercury vapor lamp that emits intense lines distributed throughout the ultraviolet and visible regions.
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Redirection and reshaping of intense extreme-ultraviolet radiation.

Science advances·2026
Same author

An agentic framework for autonomous scientific discovery in cancer pathology.

Nature medicine·2026
Same author

Up-chirped nonlinear thulium fiber amplifier delivering sub-100 fs high-energetic pulses.

Optics letters·2026
Same author

High power ultrafast phase-locked laser at 2060 nm from a doubly resonant optical parametric oscillator.

Scientific reports·2026
Same author

Fragmentation dynamics of CS2 dications and trications following S 2p ionization.

The Journal of chemical physics·2026
Same author

Gain dynamics in thulium-doped fiber amplifiers.

Optics express·2025

Related Experiment Video

Updated: Dec 23, 2025

Direct Imaging of Laser-driven Ultrafast Molecular Rotation
10:52

Direct Imaging of Laser-driven Ultrafast Molecular Rotation

Published on: February 4, 2017

10.1K

A synchronized VUV light source based on high-order harmonic generation at FLASH.

Elisa Appi1,2, Christina C Papadopoulou3, Jose Louise Mapa1,2

  • 1Institut für Quantenoptik, Leibniz Universität Hannover, Hannover, 30167, Germany.

Scientific Reports
|April 24, 2020
PubMed
Summary
This summary is machine-generated.

This study demonstrates the first successful synchronization of high-harmonic generation (HHG) and free-electron laser (FEL) sources for ultrafast extreme ultraviolet (XUV) measurements. This breakthrough enables novel two-color pump-probe experiments with femtosecond precision.

More Related Videos

Simultaneous Label-Free Autofluorescence Multi-Harmonic Microscopy
09:19

Simultaneous Label-Free Autofluorescence Multi-Harmonic Microscopy

Published on: August 29, 2025

501
Patterned Photostimulation with Digital Micromirror Devices to Investigate Dendritic Integration Across Branch Points
09:30

Patterned Photostimulation with Digital Micromirror Devices to Investigate Dendritic Integration Across Branch Points

Published on: March 2, 2011

16.1K

Related Experiment Videos

Last Updated: Dec 23, 2025

Direct Imaging of Laser-driven Ultrafast Molecular Rotation
10:52

Direct Imaging of Laser-driven Ultrafast Molecular Rotation

Published on: February 4, 2017

10.1K
Simultaneous Label-Free Autofluorescence Multi-Harmonic Microscopy
09:19

Simultaneous Label-Free Autofluorescence Multi-Harmonic Microscopy

Published on: August 29, 2025

501
Patterned Photostimulation with Digital Micromirror Devices to Investigate Dendritic Integration Across Branch Points
09:30

Patterned Photostimulation with Digital Micromirror Devices to Investigate Dendritic Integration Across Branch Points

Published on: March 2, 2011

16.1K

Area of Science:

  • Atomic, Molecular, and Optical Physics
  • Ultrafast Science
  • X-ray Science

Background:

  • Femtosecond timescale measurements in the extreme ultraviolet (XUV) region traditionally use either free electron lasers (FELs) or high-harmonic generation (HHG) sources.
  • Combining these complementary XUV sources was a significant technical challenge, limiting advanced experimental capabilities.

Purpose of the Study:

  • To demonstrate the first synchronized operation of an HHG beamline with the FLASH FEL.
  • To establish a new platform for advanced two-color pump-probe spectroscopy in the XUV region.

Main Methods:

  • Commissioning of a synchronized HHG beamline at the FL26 end-station, integrated with a reaction microscope (REMI).
  • Utilizing an optical parametric amplifier synchronized to the FEL burst mode to drive the HHG process.
  • Performing electron momentum measurements using REMI for source characterization.

Main Results:

  • Successful long-term stability of the synchronized HHG source demonstrated over 14 hours.
  • Validation of the synchronized system through electron momentum measurements.
  • First realization of a combined FEL-HHG experimental setup for ultrafast XUV studies.

Conclusions:

  • The synchronized FEL-HHG system provides a powerful new tool for ultrafast time-resolved studies.
  • This capability opens new avenues for investigating core-level ionization dynamics and molecular reaction dynamics on femtosecond timescales.
  • Enables novel research in the ultraviolet to soft X-ray spectral range.