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Updated: Dec 23, 2025

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
Published on: September 9, 2012
A Case of Acquired Factor V Deficiency in Patient with Bleeding
Davide Vetri1, Giovanni Lumera1, Salvatore Tarascio1
1Department of Clinical and Experimental Medicine, University of Catania, Catania, Sicily, Italy.
Abstract:
Low frequency of rare diseases origins from missed diagnosis addressing to poor prognosis. Acquired factor V inhibitor is a very low frequent bleeding condition (prevalence: 0.09/100,000,000-0.29/1,000,000 per year). Antibiotics, surgery, bacterial infections, malignancies, and autoimmune diseases are predisposing factors; however, no predisposing factor was found often. Authors reported a case of bleeding originating from an acquired factor V deficiency because they wish to draw attention to unfrequented or rare clinical situations rarely diagnosed in internal medicine unit.
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