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Updated: Dec 23, 2025

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis
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E2F1 Regulates Adipocyte Differentiation and Adipogenesis by Activating ICAT.

Jingqing Chen1, Yuchen Yang1, Shuai Li1

  • 1State key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100193, China.

Cells
|April 25, 2020
PubMed
Summary

E2F1 promotes pre-adipocyte differentiation by activating ICAT, which represses Wnt/β-catenin signaling. This study reveals E2F1

Keywords:
3T3-L1E2F1ICATWnt/β-cateninadipogenesisdifferentiation

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