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How could nanoallergen technology be used as a diagnostic tool for allergies?

Baksun Kim1, Jaeho Shin1, Basar Bilgicer1,2,3

  • 1Department of Chemical & Biomolecular Engineering, University of Notre Dame, Notre Dame, IN 46556, USA.

Nanomedicine (London, England)
|April 25, 2020
PubMed
Abstract

No abstract available in PubMed .

Keywords:
allergy diagnosisdegranulationdrug allergyepitopefood allergyimmunogenicitynanoallergen

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Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...

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