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Updated: Dec 23, 2025

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Aromatherapy as an adjunctive therapy for neonatal abstinence syndrome: A pilot study
John M Daniel1, Lesley N Davidson2, Jennifer R Havens3
1Clinical Assistant Professor of Pediatrics, Children's Mercy Hospitals and Clinics, Kansas City, Missouri; University of Missouri-Kansas City, School of Medicine, Kansas City, Missouri.
Objective:
To determine if aromatherapy added to the current standard of care for opioid withdrawal syndrome decreases hospitali-zation and need for opioid replacement in neonates.
Design:
Nonblinded, randomized control trial.
Setting:
Level 4 neonatal intensive care unit (NICU).
Patients And Participants:
Thirty eight patients met inclusion criteria of greater than or equal to 36 weeks of gestation, history of in-trauterine opioid exposure, primary diagnosis of neonatal abstinence syndrome (NAS), and parental permission to participate.
Interventions:
Infants were randomized to either a standard therapy group or a standard therapy plus aromatherapy.
Main Outcome Measure(S):
Duration of therapy and length of stay.
Results:
Our pilot study showed that the use of aromatherapy in conjunction with standard therapy reduced the duration of medica-tion treatment by 41 percent and hospital length of stay in the NICU by 36 percent.
Conclusions:
The use of aromatherapy appears to help mitigate symptoms of NAS and offers to be a viable treatment modality when used with conventional therapy.
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