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An overview on medication-assisted treatment (MAT) for opioid dependence
Tanay Maiti1, Saibal Das2, Anand Ramasamy3
1Department of Psychiatry, All India Institute of Medical Sciences, Bhubaneswar, India.
Abstract:
In this article, a broad overview of medication-assisted treatment (MAT) for opioid dependence has been provided. Significant benefits of commonly used drugs (buprenorphine, methadone, and naltrexone-based regimens) along with the therapeutic aspects of other available options are highlighted. Salient points on each or individual drug therapy, comparison of pharmacological profiles of dif-ferent drugs, effective clinical practice in different scenarios, relevant drug interactions, and safety issues in various populations have been emphasized. Finally, special issues, such as cost-effectiveness of different medication regimens, community-based approach, dealing with a special population, and upcoming new treatment modalities of MAT have been discussed.
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