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Primary Brainstem Angiosarcoma Mimicking Cavernous Malformation
Changik Lee1, Yong Sam Shin1, Jai Ho Choi1
1Department of Neurosurgery, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Republic of Korea.
World Neurosurgery
|April 25, 2020
Summary
This is the first reported case of brainstem angiosarcoma, a rare brain tumor. Early consideration of angiosarcoma is crucial for diagnosing rapidly progressing hemorrhagic brainstem lesions.
Area of Science:
- Neuro-oncology
- Vascular oncology
Background:
- Cerebral angiosarcoma, a rare malignant tumor originating from vascular endothelial cells, typically affects the brain or meninges.
- Primary brainstem angiosarcoma has not been previously documented in medical literature.
Observation:
- A 64-year-old male presented with symptoms including left-sided weakness, hypesthesia, and dizziness.
- Brain imaging revealed a rapidly growing, multistage hemorrhagic mass in the right dorsal pons, initially misdiagnosed as a cavernous malformation.
Findings:
- Surgical resection was performed, and subsequent pathological examination confirmed the diagnosis of brainstem angiosarcoma.
- This case represents the first documented instance of brainstem angiosarcoma confirmed via pathology post-surgical resection.
Implications:
- Clinicians should include angiosarcoma in the differential diagnosis for atypical hemorrhagic brainstem lesions exhibiting rapid progression on imaging.
- This finding underscores the importance of considering rare diagnoses in cases of unexplained neurological deterioration and complex brainstem masses.
