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Related Experiment Video

Updated: Dec 23, 2025

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
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Overnight orthokeratology.

Mark A Bullimore1, Leah A Johnson2

  • 1University of Houston, College of Optometry, 4901 Calhoun Rd., Houston, TX, 77204, United States.

Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association
|April 26, 2020
PubMed
Summary
This summary is machine-generated.

Orthokeratology lenses temporarily reduce myopia and are increasingly used for myopia control in children. This review examines their effectiveness, long-term effects, and safety.

Keywords:
Microbial keratitisMyopiaMyopia controlOvernight orthokeratologyRGP lensesSafety

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Area of Science:

  • Ophthalmology
  • Optometry
  • Corneal Reshaping

Background:

  • Orthokeratology (ortho-k) involves using rigid gas permeable contact lenses to reshape the cornea.
  • Initially used for temporary myopia reduction, ortho-k is now widely prescribed for myopia control in children.
  • Modern ortho-k lenses are sophisticated gas permeable designs that reshape the cornea to correct refractive errors.

Purpose of the Study:

  • To review the peer-reviewed literature on the efficacy of orthokeratology for myopia control.
  • To assess the sustainability of myopia control after treatment discontinuation.
  • To evaluate the safety concerns associated with overnight contact lens wear.

Main Methods:

  • Systematic review of peer-reviewed literature.
  • Analysis of studies on orthokeratology lens efficacy for myopia control.
  • Evaluation of research on treatment discontinuation and safety.

Main Results:

  • Orthokeratology lenses are approved globally for temporary myopia reduction.
  • Recent approvals in Europe specifically target myopia control in children.
  • Evidence supports ortho-k's role in slowing myopia progression and limiting axial elongation.

Conclusions:

  • Orthokeratology is an effective method for myopia control in children.
  • Further research is needed on long-term sustainability and safety.
  • Future research should explore novel lens designs and treatment protocols.