Related Experiment Video

Updated: Dec 23, 2025

Topical Airway Anesthesia for Awake-endoscopic Intubation Using the Spray-as-you-go Technique with High Oxygen Flow
05:43

Topical Airway Anesthesia for Awake-endoscopic Intubation Using the Spray-as-you-go Technique with High Oxygen Flow

Published on: January 13, 2017

17.0K

Topical preparations to reduce SARS-CoV-2 aerosolization in head and neck mucosal surgery

Harman S Parhar1, Kendall Tasche1, Robert M Brody1

  • 1Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Head & Neck
|April 26, 2020
PubMed
Abstract

Insights

Povidone-iodine (PVP-I) solutions show strong virucidal activity against coronaviruses. Preoperative application may reduce viral load and transmission risk for healthcare workers during upper airway surgery.

Area of Science:

  • Otolaryngology
  • Infectious Diseases
  • Virology

Background:

  • The COVID-19 pandemic poses risks to healthcare workers from aerosolized SARS-CoV-2 during procedures.
  • Upper airway mucosal surgeries increase potential for viral exposure and transmission.

Purpose of the Study:

  • To review topical preparations with preoperative virucidal activity.
  • To identify agents that can decrease viral load and reduce transmission risk.

Main Methods:

  • A systematic review of the PubMed/MEDLINE database was conducted.
  • Searched for topical preparations with demonstrated virucidal activity against coronaviruses.

Main Results:

  • Povidone-iodine (PVP-I) solutions (0.23%-7%) exhibit potent virucidal effects against various coronaviruses.
  • PVP-I is effective against SARS-CoV-1 and MERS-CoV.

Conclusions:

  • PVP-I preparations can reduce coronavirus viral loads.
  • While direct SARS-CoV-2 data is limited, PVP-I is a potential agent to mitigate transmission risk during upper airway surgery.
Keywords:
COVID-19SARS-CoV-2coronavirushead and neck cancersafety

More Related Videos

Author Spotlight: Advancing Awake Nasotracheal Intubation with Flexible Video Rhino-Laryngoscopes03:58

Author Spotlight: Advancing Awake Nasotracheal Intubation with Flexible Video Rhino-Laryngoscopes

Published on: August 2, 2024

1.6K
Direct Tracheal Instillation of Solutes into Mouse Lung04:50

Direct Tracheal Instillation of Solutes into Mouse Lung

Published on: August 29, 2010

29.8K

Related Concept Videos

Suctioning the Nasopharyngeal Airway01:29

Suctioning the Nasopharyngeal Airway

Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
Equipment Required
2.4K
Local Anesthetics: Common Agents and Their Applications01:23

Local Anesthetics: Common Agents and Their Applications

Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
813
Tracheostomy Suctioning I: Pre-Procedural Steps01:26

Tracheostomy Suctioning I: Pre-Procedural Steps

Tracheostomy suctioning is a critical procedure healthcare professionals perform to maintain a patent airway in patients with a tracheostomy tube. This procedure is necessary when secretions accumulate in the airway, causing respiratory distress. Here is a step-wise procedural guide for performing tracheostomy suctioning using an open system.
Equipment Required
First, gather all necessary equipment: a sterile suction catheter, a sterile disposable container, sterile gloves, a towel or...
1.8K
Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned...
421
Tracheostomy Suctioning II: Procedure01:23

Tracheostomy Suctioning II: Procedure

Tracheostomy suctioning is a vital nursing procedure that involves removing secretions from the tracheostomy tube to maintain airway patency and prevent respiratory complications. Nurses need to understand the proper technique for tracheostomy suctioning to ensure patient safety and comfort. In this guide, we will outline the step-by-step process for performing tracheostomy suctioning, including preparing the sterile field, donning personal protective equipment (PPE), lubricating and connecting...
1.2K
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques01:30

Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway...
370