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Updated: Dec 23, 2025
Monitoring of Systemic and Hepatic Hemodynamic Parameters in Mice
Published on: October 4, 2014
Invasive central venous monitoring during hepatic resection: unnecessary for most patients
David C O'Connor1, Kenneth Seier2, Mithat Gonen2
1Memorial Sloan Kettering Cancer Center, 1275 York Avenue, 10065, New York, NY, USA.
Background:
Low central venous pressure (LCVP) anesthesia reduces blood loss during hepatic resection and historically has required a central venous catheter (CVC) for intra-operative monitoring. The aim of this study was to assess the effect of an evolution of practice to CVP monitoring without CVC on the perioperative outcomes after liver resection.
Methods:
A retrospective study of partial hepatectomy patients from 2007 to 2016 who were over 18 years of age was performed.
Results:
Of 3903 patients having partial hepatectomy, 2445 (62%) met inclusion criteria, and 404 (16%) had a CVC. Overall morbidity (33% non-CVC vs 38% CVC P = 0.076), major morbidity (16% vs 20% P = 0.067), and infective complications (superficial wound infection) 3% vs 4% P = 0.429; deep wound infection (5% vs 6% P = 0.720) did not differ between the two groups. In multivariate analysis, superficial wound infection, deep wound infection, and major complications were not associated with the presence of a CVC. All-cause mortality at 90 days was associated with CVC presence (OR 3.45, CI 1.74-6.85, P = 0.001) and age (OR 1.05, CI 1.02-1.08, P < 0.001).
Conclusion:
Since the adoption of non-invasive CVP monitoring, there has been no increase in adverse peri-operative outcomes.
