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Heart Failure with Preserved Ejection Fraction and 30-Day Readmission
Manjari Rani Regmi1, Mukul Bhattarai2, Priyanka Parajuli2
1Southern Illinois University School of Medicine, Springfield, Illinois, USA mregmi81@siumed.edu manjariregmi08.mr@gmail.com.
Clinical Medicine & Research
|April 29, 2020
Summary
Heart failure with preserved ejection fraction (HFpEF) is an independent risk factor for 30-day hospital readmission. This finding suggests targeted interventions for HFpEF patients may reduce readmission rates.
Area of Science:
- Cardiology
- Healthcare Management
Background:
- Heart failure (HF) is a significant risk factor for hospital readmissions.
- Limited studies have explored the predictability of HF readmissions based on HF type.
Purpose of the Study:
- To investigate if heart failure with preserved ejection fraction (HFpEF) or heart failure with reduced ejection fraction (HFrEF) is more associated with 30-day hospital readmission rates.
- To compare the predictability of HFpEF and HFrEF against established risk scores (HOSPITAL score and LACE index).
Main Methods:
- Retrospective study of 1,916 adult patients from a single academic center (2015-2017).
- Analysis included baseline characteristics, diagnosis codes, and HF type (HFpEF vs. HFrEF).
- Multivariate logistic regression was used to identify independent risk factors for readmission.
Main Results:
- Both HOSPITAL score and LACE index significantly predicted 30-day readmissions (P < 0.001).
- HFpEF showed a significant association with readmission (P < 0.001), unlike HFrEF (P = 0.141).
- Multivariate analysis confirmed HFpEF as an independent risk factor for readmission (OR = 1.77, P = 0.001).
Conclusions:
- HFpEF is an independent risk factor for hospital readmission in academic tertiary care settings.
- Multidisciplinary management strategies targeting HFpEF could be crucial for reducing hospital readmissions.
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