Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inducible Operons: lac Operon01:25

Inducible Operons: lac Operon

1.2K
The lac operon in Escherichia coli is a model for understanding inducible gene regulation and metabolic flexibility. It integrates local control by lactose and global regulation through catabolite repression, enabling E. coli to preferentially metabolize glucose when available and switch to lactose utilization when glucose is scarce.Structure and Function of the lac OperonThe lac operon contains three structural genes: lacZ (β-galactosidase), lacY (lactose permease), and lacA...
1.2K
Operon Model01:23

Operon Model

916
The operon model represents a fundamental mechanism of gene regulation in prokaryotes, enabling coordinated expression of genes involved in related metabolic or functional pathways. Operons consist of structural genes, a promoter, and an operator, with transcription regulated by repressors, activators, and small effector molecules.Structure and Function of OperonsAn operon is a cluster of structural genes transcribed together under the control of a single promoter. The promoter region...
916
Operons02:09

Operons

53.8K
Prokaryotes can control gene expression through operons—DNA sequences consisting of regulatory elements and clustered, functionally related protein-coding genes. Operons use a single promoter sequence to initiate transcription of a gene cluster (i.e., a group of structural genes) into a single mRNA molecule. The terminator sequence ends transcription. An operator sequence, located between the promoter and structural genes, prohibits the operon’s transcriptional activity if bound by...
53.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cell painting in HepaRG cells: an interlaboratory reproducibility study.

Toxicological sciences : an official journal of the Society of Toxicology·2025
Same author

Phenotypic Profiling of 6PPD, 6PPD-quinone and Structurally Diverse Antiozonants in RTgill-W1 Cells Using the Cell Painting Assay.

Environmental science & technology letters·2025
Same author

Correction: Analysis of T-DNA alleles of flavonoid biosynthesis genes in Arabidopsis ecotype Columbia.

BMC research notes·2025
Same author

Assessing the impact of in vitro xenobiotic metabolism on estrogenic chemical bioactivity in high-throughput profiling assays.

Toxicology·2025
Same author

Incorporating Metabolic Competence into High-Throughput Profiling Assays.

Toxicological sciences : an official journal of the Society of Toxicology·2025
Same author

A combination of high-throughput in vitro and in silico new approach methods for ecotoxicology hazard assessment for fish.

Environmental toxicology and chemistry·2025

Related Experiment Video

Updated: Dec 23, 2025

Interactive Molecular Model Assembly with 3D Printing
06:15

Interactive Molecular Model Assembly with 3D Printing

Published on: August 13, 2020

10.7K

Building the lac Operon: A Guided-Inquiry Activity Using 3D-Printed Models.

Claire L Gordy1, Conner I Sandefur2, Tessa Lacara1

  • 1Department of Biological Sciences, North Carolina State University, Raleigh, NC 27695.

Journal of Microbiology & Biology Education
|April 29, 2020
PubMed
Summary

Tactile teaching tools (TTTs) using 3D printing improve learning in undergraduate biology. These inclusive tools, like a gene expression puzzle, showed significant learning gains, especially for disadvantaged students.

More Related Videos

3D Printing of Biomolecular Models for Research and Pedagogy
09:17

3D Printing of Biomolecular Models for Research and Pedagogy

Published on: March 13, 2017

24.8K
Three-dimensional Patterning of Engineered Biofilms with a Do-it-yourself Bioprinter
08:40

Three-dimensional Patterning of Engineered Biofilms with a Do-it-yourself Bioprinter

Published on: May 16, 2019

10.1K

Related Experiment Videos

Last Updated: Dec 23, 2025

Interactive Molecular Model Assembly with 3D Printing
06:15

Interactive Molecular Model Assembly with 3D Printing

Published on: August 13, 2020

10.7K
3D Printing of Biomolecular Models for Research and Pedagogy
09:17

3D Printing of Biomolecular Models for Research and Pedagogy

Published on: March 13, 2017

24.8K
Three-dimensional Patterning of Engineered Biofilms with a Do-it-yourself Bioprinter
08:40

Three-dimensional Patterning of Engineered Biofilms with a Do-it-yourself Bioprinter

Published on: May 16, 2019

10.1K

Area of Science:

  • Biology Education
  • Inclusive Learning Technologies
  • 3D Printing Applications

Background:

  • Undergraduate biology education heavily relies on visual aids, potentially excluding students with visual impairments or different learning styles.
  • Traditional visual methods may not effectively engage all learners in understanding complex biological concepts.
  • New technologies offer opportunities to create more accessible and inclusive educational materials.

Purpose of the Study:

  • To develop and assess tactile teaching tools (TTTs) for inclusive undergraduate biology education.
  • To evaluate the effectiveness of a 3D-printed gene expression puzzle as a guided inquiry learning activity.
  • To determine if TTTs disproportionately benefit disadvantaged student populations.

Main Methods:

  • Designed and implemented a 3D-printed gene expression puzzle incorporating tactile feedback (vibration) for transcriptional activation.
  • Assessed student learning gains using pre- and post-assessment scores in two distinct classroom settings.
  • Analyzed the effect size of the intervention, comparing results between an urban R1 university and a rural minority-serving institution.

Main Results:

  • Statistically significant increases in student assessment scores were observed after using the tactile gene expression puzzle.
  • The intervention demonstrated a greater effect size at the rural minority-serving institution compared to the urban R1 university.
  • Preliminary data indicate TTTs with guided inquiry benefit disadvantaged student populations.

Conclusions:

  • 3D-printed tactile teaching tools, combined with guided inquiry, can enhance learning of abstract biological concepts.
  • These inclusive tools show promise in leveling the educational playing field for diverse learners.
  • TTTs represent a valuable approach to creating more equitable and effective biology classrooms.