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Interim Guidelines on Antiviral Therapy for COVID-19
Sun Bean Kim1, Kyungmin Huh2, Jung Yeon Heo3
1Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Infection & Chemotherapy
|April 29, 2020
Summary
This guideline reviews potential antiviral and drug therapies for Coronavirus disease 2019 (COVID-19). It synthesizes in vivo, in vitro, and clinical data to inform treatment strategies beyond supportive care.
Area of Science:
- Infectious Diseases
- Virology
- Public Health
Background:
- Coronavirus disease 2019 (COVID-19) emerged in late 2019 and rapidly spread globally.
- As of April 16, 2020, Korea reported over 10,000 cases and 200 deaths.
- Clinical presentations of COVID-19 range from asymptomatic to severe conditions like pneumonia and organ failure.
Purpose of the Study:
- To provide a guideline on potentially effective antiviral and drug therapies for COVID-19.
- To inform clinicians and researchers on treatment options beyond supportive care.
- To consolidate evidence from in vivo, in vitro, and clinical studies.
Main Methods:
- Review of in vivo and in vitro research on COVID-19 therapies.
- Analysis of clinical experiences and treatment data from various countries.
- Guideline development based on synthesized scientific evidence.
Main Results:
- No standard antiviral therapy regimen is established for COVID-19.
- Supportive care remains a cornerstone of COVID-19 management.
- Various antiviral and drug therapies show potential based on preliminary research and clinical observations.
Conclusions:
- Further research and clinical trials are needed to establish definitive COVID-19 treatment protocols.
- This guideline offers a summary of current knowledge on potential therapeutic interventions.
- Evidence-based therapeutic strategies are crucial for managing the COVID-19 pandemic.
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