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Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
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Dentate Nucleus Signal Intensity Increases Following Repeated Gadobenate Dimeglumine Administrations: A Retrospective

Nghi C Nguyen1, Theodore T Molnar1, Lucas G Cummin1

  • 1From the Department of Radiology, University of Pittsburgh, UPMC Presbyterian, 200 Lothrop St, East Wing, 2nd Floor, Suite 200, Pittsburgh, PA 15213-2536 (N.C.N., T.T.M., E.K.); and Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, Pa (L.G.C.).

Radiology
|April 29, 2020
PubMed
Summary

Multiple MRI scans using gadobenate dimeglumine showed a dose-dependent increase in signal intensity in the dentate nucleus (DN) and middle cerebral peduncle (MCP). This finding suggests a linear relationship between gadobenate dimeglumine dosage and cerebral signal changes.

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