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Related Concept Videos

Post-traumatic Stress Disorder01:27

Post-traumatic Stress Disorder

371
Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
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Drug Therapy01:28

Drug Therapy

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The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
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Treatment Strategies for Psychological Disorders01:24

Treatment Strategies for Psychological Disorders

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Treatment approaches for psychological disorders fall into three main categories: psychological, biological, and sociocultural. Each approach targets different aspects of mental health, requiring varying levels of education and training.
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
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Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs01:28

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Tricyclic Antidepressants (TCAs), including Desipramine (Norpramin), Imipramine (Tofranil), Clomipramine (Anafranil), and Amitriptyline (Elavil), inhibit serotonin and norepinephrine reuptake and also block other receptors. They are used for depression, pain conditions, and insomnia. Common adverse effects include anticholinergic effects, sedation, orthostatic hypotension, and weight gain. They have a narrow therapeutic window and so require plasma-level monitoring. Abrupt discontinuation can...
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Introduction to Stress and Lifestyle01:27

Introduction to Stress and Lifestyle

443
Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
443
Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

380
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
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Evidence-based prescribing for post-traumatic stress disorder.

Jonathan I Bisson1, Amy Baker2, William Dekker2

  • 1Professor of Psychiatry, School of Medicine, Cardiff University.

The British Journal of Psychiatry : the Journal of Mental Science
|April 30, 2020
PubMed
Summary

Pharmacological treatments for post-traumatic stress disorder (PTSD) are effective when used after trauma-focused therapy. Best-evidenced medications include fluoxetine, paroxetine, sertraline, and venlafaxine for PTSD management.

Area of Science:

  • Psychiatry
  • Pharmacology
  • Clinical Psychology

Background:

  • Post-traumatic stress disorder (PTSD) is a debilitating mental health condition.
Keywords:
PTSDevidence-basedpharmacotherapyprescribing algorithmtreatment

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  • Trauma-focused psychological interventions are the primary treatment for PTSD.
  • Pharmacological options are considered as a secondary treatment approach.