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Published on: December 19, 2020
Clinical and imaging features of COVID-19
Haixia Chen1, Li Ai1, Hong Lu1
1Department of Medical Imaging, Seventh People's Hospital of Chongqing, Chongqing, Sichuan 400054, China.
Insights
This review summarizes the clinical and imaging features of coronavirus disease 2019 (COVID-19), aiding in early diagnosis and treatment. It highlights the limitations of CT scans and nucleic acid testing for COVID-19 detection.
Area of Science:
- Infectious Diseases
- Radiology
- Clinical Medicine
Background:
- Coronavirus disease 2019 (COVID-19) emerged in Wuhan, China, in December 2019.
- The highly infectious nature of COVID-19 facilitates rapid global spread.
- Key symptoms include fever, fatigue, and dry cough, with characteristic early laboratory findings.
Purpose of the Study:
- To review and synthesize published literature, guidelines, and consensus reports on COVID-19.
- To summarize the clinical and imaging characteristics of COVID-19.
- To provide a reliable basis for the early diagnosis and treatment of COVID-19.
Main Methods:
- Literature review of published studies, clinical guidelines, and expert consensus.
- Synthesis of information regarding clinical presentation and imaging findings.
- Analysis of diagnostic modalities including CT scans and nucleic acid testing.
Main Results:
- Early COVID-19 may present with normal or decreased white blood cell counts and decreased lymphocyte counts.
- CT scans are used for screening and diagnosis but have limitations in accuracy.
- Nucleic acid testing is the gold standard but exhibits low sensitivity, creating a diagnostic challenge.
Conclusions:
- A comprehensive understanding of clinical and imaging features is crucial for COVID-19 diagnosis.
- Addressing the limitations of current diagnostic methods is essential for effective patient management.
- This review aims to enhance early detection and treatment strategies for COVID-19.
Abstract:
Since December 2019, multiple cases of 2019 coronavirus disease (COVID-19) have been reported in Wuhan in China's Hubei Province, a disease which has subsequently spread rapidly across the entire country. Highly infectious, COVID-19 has numerous transmission channels and humans are highly susceptible to infection. The main clinical symptoms of COVID-19 are fever, fatigue, and a dry cough. Laboratory examination in the early stage of the disease shows a normal or decreased white blood cell count, and a decreased lymphocyte count. While CT examination serves as the screening and diagnostic basis for COVID-19, its accuracy is limited. The nucleic acid testing is the gold standard for the diagnosis of COVID-19, but has a low sensitivity is low. There is clearly a divide between the two means of examination. This paper reviews the published literature, guidelines and consensus, and summarizes the clinical and imaging characteristics of COVID-19, in order to provide a reliable basis for early diagnosis and treatment.
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