Clinical and imaging features of COVID-19

Haixia Chen1, Li Ai1, Hong Lu1

  • 1Department of Medical Imaging, Seventh People's Hospital of Chongqing, Chongqing, Sichuan 400054, China.

Radiology of Infectious Diseases (Beijing, China)
|April 30, 2020
PubMed

Insights

This review summarizes the clinical and imaging features of coronavirus disease 2019 (COVID-19), aiding in early diagnosis and treatment. It highlights the limitations of CT scans and nucleic acid testing for COVID-19 detection.

Area of Science:

  • Infectious Diseases
  • Radiology
  • Clinical Medicine

Background:

  • Coronavirus disease 2019 (COVID-19) emerged in Wuhan, China, in December 2019.
  • The highly infectious nature of COVID-19 facilitates rapid global spread.
  • Key symptoms include fever, fatigue, and dry cough, with characteristic early laboratory findings.

Purpose of the Study:

  • To review and synthesize published literature, guidelines, and consensus reports on COVID-19.
  • To summarize the clinical and imaging characteristics of COVID-19.
  • To provide a reliable basis for the early diagnosis and treatment of COVID-19.

Main Methods:

  • Literature review of published studies, clinical guidelines, and expert consensus.
  • Synthesis of information regarding clinical presentation and imaging findings.
  • Analysis of diagnostic modalities including CT scans and nucleic acid testing.

Main Results:

  • Early COVID-19 may present with normal or decreased white blood cell counts and decreased lymphocyte counts.
  • CT scans are used for screening and diagnosis but have limitations in accuracy.
  • Nucleic acid testing is the gold standard but exhibits low sensitivity, creating a diagnostic challenge.

Conclusions:

  • A comprehensive understanding of clinical and imaging features is crucial for COVID-19 diagnosis.
  • Addressing the limitations of current diagnostic methods is essential for effective patient management.
  • This review aims to enhance early detection and treatment strategies for COVID-19.

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