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Multiple Neural Tube Defects: A Case Report.

Mohammad Ahmad Jamous¹, Suleiman Shaheer Daoud¹, Abdullah Mohammad Abu-Aqoulah²

¹Department of Neurosurgery - Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.

The American Journal of Case Reports

|May 1, 2020

Summary

This case report details a rare instance of multiple neural tube defects (NTDs) in a newborn. Early surgical repair of these congenital anomalies is crucial for preventing severe complications.

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Area of Science:

Neurology
Developmental Biology
Pediatric Surgery

Background:

Neural tube defects (NTDs) arise from incomplete closure of the neural tube during embryonic development.
NTDs are typically isolated anomalies, with multiple occurrences being exceptionally rare.
Risk factors include unplanned pregnancies and inadequate folic acid intake prior to conception.

Observation:

A newborn female presented with antenatally diagnosed occipital encephalocele.
Physical examination revealed two distinct swellings: one occipital and one cervical.
Brain MRI confirmed a large occipital encephalocele and a cervical myelomeningocele.

Findings:

The infant had multiple, distinct neural tube defects, specifically an occipital encephalocele and a cervical myelomeningocele.
Both defects were surgically repaired in separate procedures.
The postoperative course was uneventful, indicating successful intervention.

Implications:

This case highlights the rare possibility of multiple NTDs.
Prompt surgical intervention for multiple NTDs is essential for optimal patient outcomes.
Emphasizes the importance of prenatal diagnosis and management of congenital anomalies.