Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

8.6K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
8.6K
B Cell Activation and Differentiation01:24

B Cell Activation and Differentiation

15.6K
The adaptive immune response, a sophisticated defense mechanism, relies on the activation and differentiation of B lymphocytes, or B cells. These processes enable our bodies to mount a tailored response against specific pathogens such as bacteria, free virus particles, toxins, and parasites.
When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...
15.6K
Primary Lymphoid Organs01:16

Primary Lymphoid Organs

14.4K
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
14.4K
Humoral Immune Responses01:36

Humoral Immune Responses

83.0K
Overview
83.0K
Functions of the Lymphatic and Immune System01:28

Functions of the Lymphatic and Immune System

6.2K
The lymphatic system plays a crucial role in bolstering our immune system. It consists of a network of lymphoid organs, lymph, and lymphatic vessels that provide structural and functional support in safeguarding the body against pathogens such as viruses and bacteria.
The primary lymphoid organs, including the bone marrow and the thymus, serve as the maturation sites for lymphocytes. Secondary lymphoid organs, like the mucosa-associated lymphoid tissue, activate these lymphocytes and serve as...
6.2K
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

83.0K
Overview
83.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sexual Dimorphism in c-Fos Networks Governing Aggression.

bioRxiv : the preprint server for biology·2026
Same author

Protein expression is associated with brain white matter in Veterans with Bipolar disorder and suicide attempts.

Brain, behavior, and immunity·2026
Same author

Leveraging machine learning and network biology approaches to predict brain gene expression from blood transcriptomes.

GigaScience·2026
Same author

Psychological stress during medical internship is associated with inflammatory signatures linked to mental health.

Brain, behavior, & immunity - health·2026
Same author

Study protocol: role of the blood-brain barrier in stress resilience: investigating new pathways towards Pharmacological augmentation of stress resilience (a PHASR-PP project study).

BMC psychology·2026
Same author

A shared transcriptional network in the nucleus accumbens supports resilience to chronic stress across sex.

bioRxiv : the preprint server for biology·2026

Related Experiment Video

Updated: Dec 22, 2025

A Mouse Model of Vascularized Heterotopic Spleen Transplantation for Studying Spleen Cell Biology and Transplant Immunity
08:04

A Mouse Model of Vascularized Heterotopic Spleen Transplantation for Studying Spleen Cell Biology and Transplant Immunity

Published on: June 11, 2019

16.7K

Brain-spleen connection aids antibody production

Flurin Cathomas, Scott J Russo

    Nature
    |May 1, 2020
    PubMed
    Summary

    No abstract available in PubMed .

    Keywords:
    ImmunologyNeuroscience

    More Related Videos

    Basement Membrane Matrix Encapsulated Cell Aggregation for Investigating Murine Spleen Tissue Formation
    07:30

    Basement Membrane Matrix Encapsulated Cell Aggregation for Investigating Murine Spleen Tissue Formation

    Published on: June 28, 2024

    1.8K
    Recombinant Retroviral Production and Infection of B Cells
    09:19

    Recombinant Retroviral Production and Infection of B Cells

    Published on: February 18, 2011

    14.5K

    Related Experiment Videos

    Last Updated: Dec 22, 2025

    A Mouse Model of Vascularized Heterotopic Spleen Transplantation for Studying Spleen Cell Biology and Transplant Immunity
    08:04

    A Mouse Model of Vascularized Heterotopic Spleen Transplantation for Studying Spleen Cell Biology and Transplant Immunity

    Published on: June 11, 2019

    16.7K
    Basement Membrane Matrix Encapsulated Cell Aggregation for Investigating Murine Spleen Tissue Formation
    07:30

    Basement Membrane Matrix Encapsulated Cell Aggregation for Investigating Murine Spleen Tissue Formation

    Published on: June 28, 2024

    1.8K
    Recombinant Retroviral Production and Infection of B Cells
    09:19

    Recombinant Retroviral Production and Infection of B Cells

    Published on: February 18, 2011

    14.5K