Related Experiment Video
Updated: Dec 22, 2025

A Free-breathing fMRI Method to Study Human Olfactory Function
Published on: July 30, 2017
Olfactory Reference Syndrome: A Case Report and Screening Tool
Yelena Chernyak1, Kristine M Chapleau2, Shariff F Tanious2
1Department of Psychiatry, Indiana University School of Medicine, 355 W. 16th St., Suite 2800, Indianapolis, IN, 46202, USA. ychernya@iupui.edu.
Abstract:
Olfactory reference syndrome (ORS) is a lesser known disorder that is related to obsessive-compulsive disorder. ORS is the obsessional and inaccurate belief that one is emitting a foul odor leading to embarrassment or concern about offending others, excessive hygiene behaviors, and social avoidance that significantly interferes with daily functioning. Although ORS is rare, it is challenging to diagnose. ORS-sufferers first seek treatment from non-psychiatric providers (e.g., dermatologists, dentists.) to alleviate the perceived odor, which frequently leads to misdiagnosis and unnecessary treatments. Additionally, because ORS-sufferers can have limited insight and ideas of reference, they can be misdiagnosed as having a psychotic or delusional disorder. We present a case report of a 42-year-old woman with ORS, and how the correct diagnosis of ORS provided with psychiatric treatment led to significant improvement in her daily functioning. We provide a literature review on the disorder as well as a short screener to assess ORS.
Related Concept Videos
Olfactory Receptors: Location and Structure
Physiology of Smell and Olfactory Pathway
The olfactory...
Olfaction
The olfactory receptors are embedded in the cilia of the...

