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Electrodiagnostic reference data for sensory nerve conduction studies in Saudi Arabia.

Mohammed H Alanazy1, Taim Muayqil, Moneera O Aldraihem

  • 1Division of Neurology, Department of Internal Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia

Neurosciences (Riyadh, Saudi Arabia)
|May 1, 2020
PubMed
Summary

This study established reference data for sensory nerve conduction studies (NCS) in healthy Saudi adults. The findings provide valuable benchmarks for diagnosing nerve conditions in the region.

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Area of Science:

  • Neurology
  • Clinical Electrophysiology

Background:

  • Nerve conduction studies (NCS) are crucial for diagnosing peripheral neuropathies.
  • Establishing regional reference data ensures accurate interpretation of NCS results.

Purpose of the Study:

  • To determine normative reference values for sensory nerve conduction studies (NCS) in a healthy Saudi Arabian population.
  • To provide essential data for clinical electrodiagnostic assessments.

Main Methods:

  • A cross-sectional study involving 127-137 healthy participants.
  • Measurement of sensory nerve action potential (SNAP) amplitude, conduction velocity (CV), and peak latency (PL).
  • Analysis of associations with age, sex, height, weight, and BMI; derivation of reference data.

Main Results:

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  • Age-adjusted prediction models were generated for SNAP amplitude for each nerve.
  • Reference data for PL and CV were derived from the pooled cohort without covariate adjustment.
  • The study successfully established reference ranges for sensory NCS parameters.

Conclusions:

  • The derived sensory NCS reference data are comparable to international standards, with minor variations.
  • These data serve as a crucial resource for neurological assessments in Saudi Arabia.
  • Further research focusing on older adult populations is recommended.